The compound
PCC1
Procyanidin C1 is one molecule, a polyphenol found in grape seeds. Cell and mouse studies are about this compound. That mouse work used a different formulation and a daily regimen.
Science
Procyanidin C1 research & science
Procyanidin C1 is a polyphenol found in grape seeds. Researchers study its effects on senescent, or “zombie”, cells. Explore the published studies, the PCC1™ formula and its laboratory reports.
- Studied compound
- Procyanidin C1, a natural senolytic
- Found in
- Grape seeds
PCC1 and Lonvi PCC1
The name is shared. The thing it points to is not.
The product
Lonvi PCC1
Lonvi PCC1 is the finished supplement: purified procyanidin C1 together with procyanidin B2 and epicatechin, carried in a phospholipid phytosome. One box is three sachets, taken on three mornings, then 27 days off. Those studies did not test this monthly formula in people.
The problem
Zombie cells
As we age, damaged cells stop clearing and start to linger. These senescent “zombie” cells release inflammatory signals that wear on the healthy tissue around them — the way one bad apple spoils the bunch.
Compounds that clear senescent cells are called senolytics. Procyanidin C1 is being studied for this activity.
This mouse study used a different formulation and a daily regimen. It does not establish lifespan benefits for people taking PCC1™.
About 5.7× better absorption
Procyanidins are notoriously hard for the body to absorb, and high-dose botanical extracts are difficult to keep clean. PCC1™ uses a purified isolate in a phospholipid (phytosome) complex. In our measurements, that delivery format achieves about 5.7× better bioavailability than standard grape-seed extract.
| Feature | Generic grape-seed extract | PCC1™ |
|---|---|---|
| Active compounds | A whole-plant extract whose procyanidin content shifts from batch to batch. | Procyanidin C1, B2 and epicatechin in a fixed, standardised ratio. |
| Absorption | Polyphenols pass through the body largely unabsorbed. | About 5.7× better bioavailability vs standard grape-seed extract, in our measurements. |
| Purity | High-dose botanical extracts are hard to control for contaminants. | A defined isolate with published SGS and Eurofins reports. |
| How you take it | Every day, indefinitely. | Three days a month, then rest. |
Laboratory reports for the tested material are published on the quality page.
1
Days 1–3
Take one sachet (three capsules) with breakfast and water each day.
2
Days 4–30
Take no PCC1™ for the next 27 days. Start your next box on day 31.
3
Before you start
One 30-day cycle per box. Speak with a qualified healthcare professional if you take medication, have a medical condition, or are pregnant or breastfeeding.